216
Participants
Start Date
September 10, 2024
Primary Completion Date
June 30, 2025
Study Completion Date
October 10, 2025
Analgesia plan for Anes. Group
For Anes. Group, hydromorphone intravenous pump (PCIA) with 0.04mg/hr and 0.2mg/hr bolus controlled administration. Rescue opioids will be given as sufentanil 5μg/hr, depending on the time of the last intraoperative administration. NSAIDs such as flurbiprofen axetil or ibuprofen will be administered as a complementary treatment option.
Analgesia plan for Surg. Group
For Surg. Group, hydromorphone intravenous pump is set with the same analgesic formula as in Anes. Group. Routine prescriptions for rescue opioids (tramadol) and NSAIDs according to pain level recommended by the pharmacy department will be administered.
Multi-modal analgesia during the surgery
Multi-modal analgesia, including intraoperative long-acting local anesthetics (ropivacaine and methylene blue), perioperative narcotic analgesics, and postoperative laxative and antibiotics. PCIA with the same analgesic formula will be applied in both groups.
RECRUITING
China-Japan Friendship Hospital, Beijing
RECRUITING
Department of Anesthesiology, Beijing
China-Japan Friendship Hospital
OTHER