Outcomes for Anesthesiologist-Led Care of Analgesic Protocol in Anorectal Surgery

NARecruitingINTERVENTIONAL
Enrollment

216

Participants

Timeline

Start Date

September 10, 2024

Primary Completion Date

June 30, 2025

Study Completion Date

October 10, 2025

Conditions
Postoperative Pain
Interventions
DRUG

Analgesia plan for Anes. Group

For Anes. Group, hydromorphone intravenous pump (PCIA) with 0.04mg/hr and 0.2mg/hr bolus controlled administration. Rescue opioids will be given as sufentanil 5μg/hr, depending on the time of the last intraoperative administration. NSAIDs such as flurbiprofen axetil or ibuprofen will be administered as a complementary treatment option.

DRUG

Analgesia plan for Surg. Group

For Surg. Group, hydromorphone intravenous pump is set with the same analgesic formula as in Anes. Group. Routine prescriptions for rescue opioids (tramadol) and NSAIDs according to pain level recommended by the pharmacy department will be administered.

PROCEDURE

Multi-modal analgesia during the surgery

Multi-modal analgesia, including intraoperative long-acting local anesthetics (ropivacaine and methylene blue), perioperative narcotic analgesics, and postoperative laxative and antibiotics. PCIA with the same analgesic formula will be applied in both groups.

Trial Locations (2)

100029

RECRUITING

China-Japan Friendship Hospital, Beijing

RECRUITING

Department of Anesthesiology, Beijing

All Listed Sponsors
lead

China-Japan Friendship Hospital

OTHER