Twins MR Imaging Study

Enrolling by invitationOBSERVATIONAL
Enrollment

2,500

Participants

Timeline

Start Date

December 19, 2023

Primary Completion Date

March 31, 2028

Study Completion Date

March 31, 2028

Conditions
Aging
Interventions
PROCEDURE

Magnetic Resonance Imaging

"1. A single (≤45 minutes) brain MRI will include T1w and T2w imaging to assess the morphology and structure of the brain, as well as inflammatory processes. Diffusion-weighted imaging will be used to gain information about internal brain connectivity related to brain functions. MRI, MR angiography (MRA) and fMRI pulse sequences will also be acquired to detect vascular pathologies and brain lesions. T2w morphological images of the whole spine will also be obtained.~2. A single (≤45 minutes) MR imaging investigation to include cardiovascular, abdominal, and musculoskeletal regions. MRI will be performed to assess the structure and function of these body regions and organs, including functional imaging of the heart. These investigations will include T1w and T2w imaging to assess morphology and structure, mapping studies of T1, T2 and T2\*, perfusion imaging and cine imaging to assess the heart dynamically."

Trial Locations (1)

SE1 7EH

King's College London, London

All Listed Sponsors
collaborator

Guy's and St Thomas' NHS Foundation Trust

OTHER

lead

King's College London

OTHER