A Trial to Assess Cobicistat Boosted Venetoclax in Combination With Azacitidine in Adult Patients With Newly Diagnosed AML

PHASE2RecruitingINTERVENTIONAL
Enrollment

142

Participants

Timeline

Start Date

January 17, 2024

Primary Completion Date

March 31, 2028

Study Completion Date

March 31, 2028

Conditions
AML, Adult
Interventions
DRUG

azacitidine

during run-in and extention phase: from Cycle 1 until relapse

DRUG

Venetoclax

during run-in and extention phase: from Cycle 1 until relapse

DRUG

Cobicistat

"during run-in phase: from cycle 2 until relapse~during extension phase: from cycle 1 until relapse"

Trial Locations (18)

Unknown

NOT_YET_RECRUITING

NL-Amersfoort-MEANDERMC, Amersfoort

NOT_YET_RECRUITING

NL-Amsterdam-OLVG, Amsterdam

NOT_YET_RECRUITING

NL-Amsterdam-VUMC, Amsterdam

NOT_YET_RECRUITING

NL-Arnhem-RIJNSTATE, Arnhem

NOT_YET_RECRUITING

NL-Breda-AMPHIA, Breda

NOT_YET_RECRUITING

NL-Dordrecht-ASZ, Dordrecht

NOT_YET_RECRUITING

NL-Eindhoven-CATHARINA, Eindhoven

NOT_YET_RECRUITING

NL-Eindhoven-MAXIMAMC, Eindhoven

NOT_YET_RECRUITING

NL-Enschede-MST, Enschede

RECRUITING

NL-Groningen-UMCG, Groningen

NOT_YET_RECRUITING

NL-Leeuwarden-MCL, Leeuwarden

NOT_YET_RECRUITING

NL-Leiden-LUMC, Leiden

NOT_YET_RECRUITING

NL-Maastricht-MUMC, Maastricht

NOT_YET_RECRUITING

NL-Nieuwegein-ANTONIUS, Nieuwegein

NOT_YET_RECRUITING

NL-Nijmegen-CWZ, Nijmegen

NOT_YET_RECRUITING

NL-Rotterdam-ERASMUSMC, Rotterdam

NOT_YET_RECRUITING

NL-Den Haag-HAGA, The Hague

NOT_YET_RECRUITING

NL-Zwolle-ISALA, Zwolle

All Listed Sponsors
lead

Stichting Hemato-Oncologie voor Volwassenen Nederland

OTHER