Randomized Controlled Study of Programmed Weaning From NIV for AECOPD

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

May 12, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Acute Exacerbation of COPD
Interventions
OTHER

Programmed Weaning From Noninvasive Mechanical Ventilation

Programmed withdrawal unit: daily morning review arterial blood gas analysis (since the 2nd, daily morning stop non-invasive ventilation 1 hours, 2 hours, 3 hours, 4 hours after check arterial blood gas analysis), blood gas results suggest respiratory acidosis compensatory period (pH value greater than 7.35) can reduce daily noninvasive ventilation time, namely the noninvasive ventilation use time for 24 hours, 20 hours, the third day 16 hours, the fourth 12 hours, fifth day 8 hours. If ABG indicates still acid decompensation, continue the non-invasive ventilation regimen of the previous day. If noninvasive ventilation failed, invasive mechanical ventilation was performed.

Trial Locations (1)

100191

RECRUITING

Peking University Third Hospita, Beijing

All Listed Sponsors
lead

Peking University Third Hospital

OTHER