Effect of Esmolol on Oxygenation Index in Patients With Acute Respiratory Distress Syndrome

PHASE3RecruitingINTERVENTIONAL
Enrollment

178

Participants

Timeline

Start Date

February 20, 2023

Primary Completion Date

April 30, 2026

Study Completion Date

October 30, 2026

Conditions
Acute Respiratory Distress Syndrome
Interventions
DRUG

Esmolol

The load dose of esmolol was first injected intravenously: 0.5mg/kg.min, for about 1 minute; then the maintenance dose was pumped intravenously: from 0.05mg/kg/min, and continued after 4 minutes if the efficacy was ideal; if the efficacy was poor, the load dose could be repeated and the maintenance dose increased by 0.05mg/kg/min. The maintenance dose should not exceed 0.3mg/kg/min.

Trial Locations (1)

250014

RECRUITING

Department of Intensive Care Medicine, Jinan

All Listed Sponsors
lead

Zhiming Jiang

OTHER