The Dose Range of Remimazolam Besylate in Different Age Groups

NARecruitingINTERVENTIONAL
Enrollment

1,876

Participants

Timeline

Start Date

July 17, 2023

Primary Completion Date

September 30, 2025

Study Completion Date

December 31, 2025

Conditions
RemimazolamAnesthesia
Interventions
DRUG

Remimazolam besylate

"Age 45-64: Remimazolam Besylate 0.3 mg/kg for anesthesia induction (0.05mg/kg for additional need) and 0.5mg/kg/h for maintenance (0.25 mg/kg/h for additional need).~Age over 65: Remimazolam Besylate 0.15 mg/kg for anesthesia induction (0.05mg/kg for additional need) and 0.5mg/kg/h for maintenance (0.25 mg/kg/h for additional need)."

DRUG

Propofol

"Age 45-64: Propofol 3.0μg/ml TCI for anesthesia induction and 2.5-3.0μg/ml TCI for maintenance.~Age over 65: Propofol 1.5-2.5μg/ml TCI for anesthesia induction and 1.5-2.5μg/ml TCI for maintenance"

Trial Locations (1)

430030

RECRUITING

ongji Hospital, Tongji Medical College, Huazhong Science and Technology University, Wuhan

All Listed Sponsors
collaborator

Renmin Hospital of Wuhan University

OTHER

collaborator

Wuhan University

OTHER

collaborator

The General Hospital of Central Theater Command

OTHER

collaborator

Taihe Hospital

OTHER

collaborator

Yichang Central People's Hospital

OTHER

collaborator

Jingzhou Central Hospital

OTHER

collaborator

Beijing Shijitan Hospital, Capital Medical University

OTHER

collaborator

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

OTHER

collaborator

First Affiliated Hospital of Fujian Medical University

OTHER

collaborator

Tianjin Nankai Hospital

OTHER

collaborator

Sichuan Provincial People's Hospital

OTHER

collaborator

Shanxi Bethune Hospital

OTHER

lead

Tongji Hospital

OTHER