Pain in Parkinson's Disease: Exploration of the Serotonin System in Positron Emission Tomography (PET [18F]-MPPF)

The clinical assessment consists on behavioural and motor evaluations to determine the characteristics of the population

The pain characteristics assessment will be made with a variety of scales and questionnaires which allow to identify the extent of central pain and functional impairment

The MRI examination allows anatomical imaging, diffusion imaging and functional imaging to measure specific markers

The thermotest is performed to assess the pain perception threshold

The UPDRS-III scale allows to asses motor functionality of PD patients

The PET scan after injection of \[18F\]-MPPF at a dose of 200 Megabecquerel/kg +/-10% allows in vivo imaging of 5HT1A receptors