Pharmacokinetic Characterization of a Single 200 mg Dose of Doxycycline in Post-exposure Prophylaxis (PEP) of Sexually Transmitted Infections in Different Biological Compartments

NARecruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

October 25, 2023

Primary Completion Date

April 25, 2025

Study Completion Date

April 25, 2025

Conditions
Post-exposure ProphylaxisSexually Transmitted DiseasesDoxycycline
Interventions
OTHER

Samples

Blood samples, urine samples and oropharyngeal swabs before taking 200mg of doxycycline and then 2h, 24h, 48h, 7 days, 14 days, 60 days and 90 days after the single dose of doxycycline Hair samples: at the time of doxycycline administration, 1 month and 3 months after the single dose of doxycycline

Trial Locations (2)

Unknown

RECRUITING

Hôpital Lariboisière AP-HP, Paris

RECRUITING

Hôpital Saint Louis AP-HP, Paris

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER