Right Ventricular Dysfunction in Chronic Heart Failure

Not yet recruitingOBSERVATIONAL
Enrollment

1,000

Participants

Timeline

Start Date

September 1, 2023

Primary Completion Date

March 1, 2024

Study Completion Date

September 1, 2026

Conditions
Chronic Heart FailureRight Ventricular DysfunctionRight Heart Failure
Interventions
DIAGNOSTIC_TEST

Echocardiography

Patients will undergo echocardiographic examination. The ejection fraction will be calculated using Simpson's method. The E/e' ratio will be measured using the Doppler method. E/e' \> 13 will be considered an expression of the increase in LVFP. TAPSE will be measured together with the peak tricuspid regurgitation velocity (TVR). Pulmonary arterial hypertension will be defined as TVR \> 2.8 m/s. Estimation of right atrial pressure (eRAP) will be obtained based on the diameter and inspiratory collapsibility of the inferior vena cava.

DIAGNOSTIC_TEST

Laboratory Test

BNP, NT-proBNP and renal function.

Trial Locations (14)

20127

Ospedale Sant'Agostino Milano, Milan

20138

Centro Cardiologico Monzino, Milan

27100

Fondazione IRCCS Policlinico San Matteo - Pavia UOC Cardiologia 1, Pavia

53100

Unità di Malattie Cardiovascolari, Dipartimento Cardio-Toraco-Vascolare AOUS, Università degli Studi, Siena., Siena

71121

SC Universitaria di Cardiologia - UTIC Policlinico Riuniti Foggia, Foggia

80131

Department of Translational Medical Sciences, CIRCET, Napoli

Department of Translational Medical Sciences, Federico II University, CIRCET, Napoli

Heart Failure Unit, Department of Cardiology, AORN dei Colli-Monaldi, Napoli

84084

Department of Medicine, Surgery and Dentistry, Università di Salerno, Fisciano

85100

SC Cardiologia, Azienda Ospedaliera Ospedale San Carlo Potenza, Potenza

98125

Department of Clinical and Experimental Medicine, Operativee Unit of Cardiology, University of Messina, Messina

06100

S. Maria della Misericordia Hospital, Perugia

00161

Cardiology, Department of Clinica, Internal, Anesthesiology and Cardiovascular Scienses, Sapienza., Roma

Cardiology, Department of Clinica, Internal, Anesthesiology and Cardiovascular Scienses., Roma

All Listed Sponsors
collaborator

Italian Society of Cardiology

OTHER

lead

University of Siena

OTHER

NCT06002321 - Right Ventricular Dysfunction in Chronic Heart Failure | Biotech Hunter | Biotech Hunter