A Comparative Analysis of 4% Chlorhexidine Versus Methylated Spirit as Prophylaxis of Omphalitis and Sepsis in Newborns

PHASE2CompletedINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

September 12, 2020

Primary Completion Date

September 22, 2021

Study Completion Date

November 19, 2021

Conditions
Neonatal SepsisOmphalitis
Interventions
DRUG

Chlorhexidine Topical Cream

"After approval from the hospital ethical committee, neonates fulfilling inclusion and exclusion criteria were selected. Written informed consent was obtained from the parents. Full instructions to avoid confounding variables like maintaining temperature and hygiene of newborn, frequent diaper change, avoidance of herbal tonics and cow milk; are given to mothers.~In group A 4% chlorhexidine was applied generously over cord along with base of cord stump and surrounding skin thrice a day. In group B clean cotton swab dipped in methylated spirit was used to clean cord along with cord clamps and base thrice a day."

DRUG

Methylated Spirit

"After approval from the hospital ethical committee, neonates fulfilling inclusion and exclusion criteria were selected. Written informed consent was obtained from the parents. Full instructions to avoid confounding variables like maintaining temperature and hygiene of newborn, frequent diaper change, avoidance of herbal tonics and cow milk; are given to mothers.~In group A 4% chlorhexidine was applied generously over cord along with base of cord stump and surrounding skin thrice a day. In group B clean cotton swab dipped in methylated spirit was used to clean cord along with cord clamps and base thrice a day."

Trial Locations (1)

54500

Sheikh Zayed Federal Postgraduate Medical Institute, Lahore

All Listed Sponsors
lead

Sheikh Zayed Federal Postgraduate Medical Institute

OTHER

NCT06002295 - A Comparative Analysis of 4% Chlorhexidine Versus Methylated Spirit as Prophylaxis of Omphalitis and Sepsis in Newborns | Biotech Hunter | Biotech Hunter