Comparison Between Ultrasound-Guided Genicular Nerve Phenol Neurolysis and Intra-articular Steroid Injections

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

October 20, 2023

Primary Completion Date

January 31, 2024

Study Completion Date

July 31, 2024

Conditions
Osteoarthritis, KneeChronic Knee Pain
Interventions
DRUG

6% aqueous phenol

1.5 mL of aqueous phenol will be injected at each target genicular nerve under ultrasound guidance

DRUG

MethylPREDNISolone 40 MG

40 mg of methylprednisolone diluted in 5 mL of 0.9% normal saline will be injected inside the knee joint capsule under ultrasound guidance

DRUG

Intraarticular Knee Placebo

Single injection 1.5 mL of 0.9% normal saline outside the knee joint capsule under ultrasound guidance

DRUG

Genicular Nerve Placebo

1.5 mL of 0.9% normal saline will be injected subcutaneously at each target genicular nerve under ultrasound guidance

All Listed Sponsors
lead

University of Manitoba

OTHER