100
Participants
Start Date
January 25, 2025
Primary Completion Date
December 1, 2025
Study Completion Date
January 1, 2026
superficial parasternal intercostal plane block
Injection of 60 mL of bupivacaine 0.25% and epinephrine 2.5 µg mL-1
Standard care
"Operating Room:~Anaesthesia will be induced using midazolam (0.1-0.15 mg kg-1), fentanyl (5-10 μg kg-1), and rocuronium (0.6-1.2 mg kg-1); then, after tracheal intubation, anaesthesia will be maintained using isoflurane at one MAC, along with continuous fentanyl (3-5 μg kg-1 h-1) and midazolam (20-50 μg kg-1 h-1). Additional boluses of fentanyl will be administered according to the anesthesiologist's discretion.~Cardiothoracic Intensive Care Unit:~Continuous fentanyl will be maintained until tracheal extubation. All patients will receive intravenous multimodal analgesic drugs around the clock, including paracetamol 3 g day-1 and dipyrone 3 g day-1. If pain persists, rescue doses of either intravenous tramadol or morphine will be administered.~Cardiothoracic ward:~The analgesic protocol includes around-the-clock intravenous paracetamol 3 g day-1 and dipyrone 3 g day-1. If pain continues, rescue doses of oral oxycodone will be administered."
RECRUITING
Rabin Medical Center, Beilinson Hospital, Petah Tikva
NOT_YET_RECRUITING
Rabin Medical Center, Petah Tikva
Shai Fein
OTHER