Optimizing Early Nutrition Support in Severe Stroke-2

PHASE3RecruitingINTERVENTIONAL
Enrollment

546

Participants

Timeline

Start Date

December 20, 2023

Primary Completion Date

July 31, 2026

Study Completion Date

October 31, 2026

Conditions
Severe StrokeAcute StrokeDysphagia
Interventions
PROCEDURE

Trophic enteral feeding combined with supplemental parenteral nutrition

The caloric goal of the first day is one-third of caloric requirements, the second day is half of caloric requirements, the third day is 70-100% and sustained for 1 week. Patients will receive the trophic enteral feeding with a caloric target of 500kcal/d (20-35ml/h), and the remaining calories are supplemented by parenteral nutrition. Protein requirements are calculated at 1.2 to 1.5 g per kilogram of body weight per day.

PROCEDURE

Full enteral feeding

The caloric goal of the first day is one-third of caloric requirements, the second day is half of caloric requirements, the third day is 70-100% and sustained for 1 week. Protein requirements are calculated at 1.2 to 1.5 g per kilogram of body weight per day. Enteral nutrition is given through nasogastric tube or nasointestinal tube.

Trial Locations (30)

252000

RECRUITING

Liaocheng People's Hospital, Liaocheng

330000

RECRUITING

The Second Affiliated Hospital of Nanchang University, Nanchang

404100

RECRUITING

Chongqing University Three Gorges Hospital, Chongqing

550000

RECRUITING

The Affiliated Hospital of Guizhou Medical University, Guiyang

710000

RECRUITING

Shaanxi Second Provincal People's Hospital, Xi'an

NOT_YET_RECRUITING

Tangdu Hospital, Xi'an

RECRUITING

The first affiliated hospital of Xi'an Jiaotong University, Xi'an

NOT_YET_RECRUITING

Xi'an Central Hospital, Xi'an

712000

RECRUITING

Xianyang Hospital, Yan'an University, Xianyang

750000

RECRUITING

General Hospital of Ningxia Medical University, Yinchuan

830000

RECRUITING

People's Hospital of Xinjiang Uygur Autonomous Region, Ürümqi

RECRUITING

The Second Affiliated Hospital of Xinjiang Medical University, Ürümqi

Unknown

RECRUITING

Daping Hospital, The Third Military Medical University, Chongqing

RECRUITING

Gansu Provincal Central Hospital, Lanzhou

NOT_YET_RECRUITING

Nanfang Hospital, Southern Medical University, Guangzhou

RECRUITING

The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou

RECRUITING

First Affiliated Hospital of Zhengzhou University, Zhengzhou

RECRUITING

Tongji Hospital, Wuhan

NOT_YET_RECRUITING

The First Hospital of Changsha City, Changsha

RECRUITING

Department of Neurology, Xijing Hospital, Xi'an

NOT_YET_RECRUITING

Shannxi Provincal People's Hospital, Xi'an

RECRUITING

The First Affiliated Hospital of Xi'an Medical University, Xi'an

RECRUITING

Xi'an Gaoxin Hospital, Xi'an

RECRUITING

Xi'an No.3 Hospital, Xi'an

RECRUITING

The First People's Hospital of Xianyang, Xianyang

NOT_YET_RECRUITING

Yulin No.1 Hospital, Yulin

NOT_YET_RECRUITING

Yulin No.2 Hospital, Yulin

NOT_YET_RECRUITING

Qilu Hospital of Shangdong University, Jinan

RECRUITING

The PLA 960 Hospital, Jinan

RECRUITING

The Second Hospital of Shandong University, Jinan

All Listed Sponsors
collaborator

Tang-Du Hospital

OTHER

collaborator

Xi'an Central Hospital

OTHER

collaborator

Xi'an Gaoxin Hospital

OTHER

collaborator

First Affiliated Hospital Xi'an Jiaotong University

OTHER

collaborator

Xi'an No.3 Hospital

OTHER_GOV

collaborator

First People's Hospital of Xianyang

OTHER

collaborator

Nanfang Hospital, Southern Medical University

OTHER

collaborator

Tongji Hospital

OTHER

collaborator

Qilu Hospital of Shandong University

OTHER

collaborator

The Second Hospital of Shandong University

OTHER

collaborator

PLA 960 Hospital

UNKNOWN

collaborator

Daping Hospital, The Third Military Medical University (Army Medical University)

UNKNOWN

collaborator

The Second Affiliated Hospital of Guangzhou University of Chinese Medicine

UNKNOWN

collaborator

First Hospital Affiliated to Zhengzhou University

UNKNOWN

collaborator

Gansu Provincial Central Hospital

UNKNOWN

collaborator

The First Hospital of Changsha City

UNKNOWN

collaborator

Shaanxi Provincial People's Hospital

OTHER

collaborator

Yulin No.2 Hospital

OTHER

collaborator

Yulin No.1 Hospital

UNKNOWN

collaborator

Xijing Hospital

OTHER

lead

Wen Jiang-3

OTHER