NCT05990790View on ClinicalTrials.gov

The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium

PHASE4RecruitingINTERVENTIONAL
Enrollment

1,332

Participants

Timeline

Start Date

September 3, 2023

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2028

Conditions
Postoperative DeliriumMajor Noncardiac SurgeryPostoperative Cognitive Dysfunction
Interventions
DRUG

Desflurane

After induction of anesthesia, maintenance of anesthesia will be performed using goal-directed administration of desflurane with an intraoperative goal of bispectral index (BIS) 50±10.

DRUG

Sevoflurane

After induction of anesthesia, maintenance of anesthesia will be performed using goal-directed administration of sevoflurane with an intraoperative goal of bispectral index (BIS) 50±10.

DRUG

Propofol

After induction of anesthesia, maintenance of anesthesia will be performed using goal-directed administration of propofol with an intraoperative goal of bispectral index (BIS) 50±10.

Trial Locations (2)

1090

RECRUITING

Medical University of Vienna, Vienna

6020

RECRUITING

Medical University of Innsbruck, Innsbruck

All Listed Sponsors
collaborator

Medical University Innsbruck

OTHER

lead

Medical University of Vienna

OTHER