Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

April 29, 2023

Primary Completion Date

September 29, 2025

Study Completion Date

December 29, 2025

Conditions
Surgical Site InfectionSurgical WoundSurgical IncisionEmergency LaparotomiesLaparotomiesPost Operative Wound InfectionWound InfectionSeroma
Interventions
PROCEDURE

0.9% saline solution

During emergency laparotomy, after the primary surgical procedure. the sheath will be sutured and the incision site will then be irrigated with three rounds of 1 liter of 0.9% saline solution, which will be completely aspirated before the closure of the incisional wound in experimental group.

PROCEDURE

Povidone-iodine Swab

No intra-operative wound lavage done, and wound would be cleaned with povidone doused swab.

Trial Locations (1)

74400

RECRUITING

Dr. Ruth K. M. Pfau Civil Hospital Karachi, Karachi

All Listed Sponsors
lead

Dow University of Health Sciences

OTHER