316
Participants
Start Date
September 22, 2023
Primary Completion Date
December 30, 2025
Study Completion Date
December 30, 2025
Transvaginal ultrasound
Transvaginal ultrasound throughout the HRT cycle to not only monitor endometrial development but to also exclude the presence of an ovarian dominant follicle
Serum LH, E2, P4
In conjunction with ultrasound monitoring, participants will undergo serial measurements of serum Luteinizing Hormone (LH), Estradiol (E2) and Progesterone (P4) levels
Estradiol Valerate 2 MG
"Participants will commence estradiol valerate 4 mg ( 2 x 2 mg) on day 2 / day 3 of menses.~Estradiol will be increased to 6 mg on day 2 of estrogen treatment, and continued at a daily dose of 6 mg (3 tablets daily)"
Progesterone 100 Mg Vaginal Insert
The initial progesterone dose of 100 mg will be commenced at 13hrs and repeated at 21hrs considered day 1 (vaginal suppository) when an optimal endometrial thickness for each participant has been achieved with a trilaminar appearance. The following day (day 2) progesterone administration will be increased to 100 mg vaginally three times daily
Serum P4 day of ET
On the day of embryo transfer (ET), a blood test is taken to measure serum P4
Embryo transfer
Procedure in which embryo is transferred into the uterus
RECRUITING
ART Fertility Clinics LLC, Abu Dhabi
RECRUITING
ART Fertility Clinics Dubai, Dubai
ART Fertility Clinics LLC
OTHER