Randomized Evaluation of Machine Learning Assisted Radiation Treatment Planning vs Standard Radiation Treatment Planning

NAActive, not recruitingINTERVENTIONAL
Enrollment

204

Participants

Timeline

Start Date

August 7, 2023

Primary Completion Date

December 16, 2025

Study Completion Date

December 16, 2025

Conditions
Cancer Head NeckCancer, HeadCancer Neck
Interventions
RADIATION

Machine Learning Assisted Radiation (MLAP) RapidPlan

Radiation therapy simulation, target delineation, dosing, localization, and follow-up will be followed per standard of care practices and/or at the discretion of the treating radiation oncologist. To elaborate, patients will receive a treatment planning CT (computed tomography) scan, followed by normal tissue delineation through the physician and/or medical dosimetry assistant, followed by target delineation by the physician, followed by radiation treatment planning with the dosimetrist and medical physicist. The preliminary plan will be run through the RapidPlan module, which will give a list of possible improvements to the plan. The dosimetrist will then make an amendment to the plan according to RapidPlan suggestions, followed by plan change requests and approval by the physician.

RADIATION

Radiation Therapy Standard of Care (SOC)

Radiation therapy simulation, target delineation, dosing, localization, and follow-up will be followed per standard of care practices and/or at the discretion of the treating radiation oncologist. To elaborate, patients will receive a treatment planning CT (computed tomography) scan, followed by normal tissue delineation through the physician and/or medical dosimetry assistant, followed by target delineation by the physician, followed by radiation treatment planning with the dosimetrist and medical physicist, followed by plan change requests and approval by the physician.

Trial Locations (6)

32224

Mayo Clinic in Florida, Jacksonville

54601

Mayo Clinic Health System-Franciscan Healthcare, La Crosse

54701

Mayo Clinic Health System-Eau Claire Clinic, Eau Claire

56001

Mayo Clinic Health Systems-Mankato, Mankato

56007

Mayo Clinic Health System in Albert Lea, Albert Lea

85259

Mayo Clinic in Arizona, Scottsdale

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER

NCT05979883 - Randomized Evaluation of Machine Learning Assisted Radiation Treatment Planning vs Standard Radiation Treatment Planning | Biotech Hunter | Biotech Hunter