7
Participants
Start Date
May 10, 2023
Primary Completion Date
August 31, 2027
Study Completion Date
August 31, 2027
PEEP (positive end-expiratory pressure) - maximum
"Breathing assistance from the breathing assist machine using a method in which doctors try to find the pressures that expands the lungs the best. This is based on measurements of one's respiratory pressures and volumes. This is done by adjusting the pressure settings. This allows one's lungs to expand with the least amount of change in pressure during breathing.~PEEP (positive end-expiratory pressure) will be set at the maximum static respiratory system compliance (Crs) during a descending PEEP titration curve."
PEEP (positive end-expiratory pressure) - standard
"Breathing assistance from the breathing assist machine using the pressure settings typical for your disease.~Standard ARDSNet low-stretch PEEP (positive end-expiratory pressure) protocol: PEEP will be set following a routinely used PEEP table according to patients' blood oxygenation status."
Columbia University, New York
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Columbia University
OTHER