A Clinical Study of TQB2618 Injection Combined With Penpulimab Injection and Anlotinib Hydrochloride Capsules for First-line Treatment of Advanced Hepatocellular Carcinoma (HCC).

PHASE1TerminatedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

August 15, 2023

Primary Completion Date

June 4, 2025

Study Completion Date

June 4, 2025

Conditions
Advanced Hepatocellular Carcinoma
Interventions
DRUG

Penpulimab injection

Penpulimab is an inhibitor of programmed cell death 1 (PD-1).

DRUG

TQB2618 injection

TQB2618 injection is an inhibitor of T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3).

DRUG

Anlotinib Hydrochloride Capsules

Anlotinib hydrochloride is a muti-target tyrosine kinase inhibitor.

Trial Locations (8)

110000

The six people's Hospital of Shenyang, Shenyang

150000

Affiliated Cancer Hospital of Harbin Medical University, Harbin

200433

Third Affiliated Hospital of Naval Medical University, Shanghai

410031

Hunan Cancer Hospital, Changsha

476100

The First People's Hospital of Shangqiu City, Shangqiu

510600

The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou

563099

Affiliated hospital of zunyi medical university, Zunyi

733099

Gansu Wuwei Cancer Hospital, Wuwei

All Listed Sponsors
lead

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

INDUSTRY