A Clinical Study to Evaluate the Efficacy and Safety of Subcutaneous JS005 Injection in the Treatment of Adults With Moderate to Severe Chronic Plaque Psoriasis

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

747

Participants

Timeline

Start Date

August 28, 2023

Primary Completion Date

August 18, 2025

Study Completion Date

October 29, 2025

Conditions
Moderate to Severe Chronic Plaque Psoriasis
Interventions
BIOLOGICAL

JS005 (recombinant humanized monoclonal antibody against IL-17A)

JS005/placebo

Trial Locations (63)

100044

Beijing Friendship Hospital, Capital Medical University, Beijing

Beijing Tongren Hospital Affiliated to Capital Medical University, Beijing

China-Japan Friendship Hospital, Beijing

Peking University People's Hospital, Beijing

Peking University Third Hospital, Beijing

100864

Ningbo Huamei Hospital, University of Chinese Academy of Sciences, Beijing

101199

Beijing LuHe Hospital Capital Medical University, Beijing

102218

Beijing Tsinghua Changgung Hospital, Beijing

110004

Shengjing Hospital affiliated to China Medical University, Shenyang

110021

Shenyang Hospital of Integrated Chinese and Western Medicine, Shenyang

124011

Panjin Liao oil precious stone flower hospital, Panjin

130021

Bethune First Hospital of Jilin University, Changchun

200050

Shanghai Dermatology Hospital, Shanghai

212000

Affiliated Hospital of Jiangsu University, Zhenjiang

214002

Wuxi Second People's Hospital, Wuxi

215123

The First Affiliated Hospital of Soochow University, Suzhou

222002

Lianyungang First People's Hospital, Lianyungang

224006

Yancheng First People's Hospital, Yancheng

230601

The Second Affiliated Hospital of Anhui Medical University, Hefei

233004

The First Affiliated Hospital of Bengbu Medical College, Bengbu

250000

Shandong Dermatology Hospital, Jinan

250013

Jinan Central Hospital, Jinan

300120

Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin

310002

Hangzhou Third People's Hospital, Hangzhou

310006

Hangzhou First People's Hospital, Hangzhou

310014

Zhejiang Provincial People's Hospital, Hangzhou

310016

Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou

314001

The First Hospital of Jiaxing, Jiaxing

325000

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou

330000

Jiangxi Dermatology Hospital, Nanchang

330006

The Second Affiliated Hospital of Nanchang University, Nanchang

341000

The First Affiliated Hospital of Gannan Medical College, Ganzhou

350005

The First Affiliated Hospital of Fujian Medical University, Fuzhou

361023

The Second Affiliated Hospital of Xiamen Medical College, Xiamen

400016

The First Affiliated Hospital of Chongqing Medical University, Chongqing

410008

The Second Xiangya Hospital, Central South University, Changsha

410013

Xiangya Third Hospital, Central South University, Changsha

430060

Wuhan University People's Hospital, Wuhan

434020

Jingzhou Central Hospital, Jingzhou

442000

Shiyan City People's Hospital, Shiyan

453100

The First Affiliated Hospital of Xinxiang Medical College, Xinxiang

473000

Nanyang city first People's Hospital, Nanyang

510080

Guangdong General Hospital, Guangzhou

510091

Dermatology Hospital of Southern Medical University, Guangzhou

510180

Guangzhou First People's Hospital, Guangzhou

518020

Shenzhen People's Hospital, Shenzhen

518107

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou

523018

Dongguan People's Hospital, Dongguan

610017

Chengdu Second People's Hospital, Chengdu

610041

West China Hospital of Sichuan University, Chengdu

629000

Suining Central Hospital, Suining

650118

The Second Affiliated Hospital of Kunming Medical University, Kunming

710004

Medicine School of Xi'an Jiaotong University, Xian

710061

The First Affiliated Hospital of Xi 'an Jiaotong University City:Xian, Xi’an

730030

Lanzhou University Second Hospital, Lanzhou

750004

Ningxia Medical University General Hospital, Yinchuan

Unknown

The Affiliated Hospital of Chengde Medical College, Chengde

North East Central International Hospital Limited, Shenyang

050000

The First Hospital of Hebei Medical University, Shijiazhuang

054031

Xingtai People's Hospital, Xingtai

014040

Baotou Central Hospital, Baotou

010000

Inner Mongolia Baotou Steel Hospital, Baotou

030001

The Second Hospital of Shanxi Medical University City:Taiyuan, Taiyuan

All Listed Sponsors
lead

Shanghai Junshi Bioscience Co., Ltd.

OTHER

NCT05975268 - A Clinical Study to Evaluate the Efficacy and Safety of Subcutaneous JS005 Injection in the Treatment of Adults With Moderate to Severe Chronic Plaque Psoriasis | Biotech Hunter | Biotech Hunter