V5/MT Stimulation on Reading and Reading-related Measures in Developmental Dyslexia

NARecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

September 1, 2023

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions
Developmental Dyslexia
Interventions
DEVICE

Active HD-tDCS over V5/MT

For HD-tDCS a 4 × 1 montage (Kessler et al., 2013), small circular electrodes (diameter 1 cm) will be used with the anode placed centrally with a current intensity of 1 mA for a total of 20 minutes (30 s ramp up/down). Hereby, the anodal electrode modulates the excitability of the targeted area left V5/MT, whereas the other 4 electrodes return electrical currents that flow away from that area. V5/MT will be localised via published procedures and electrode's placement will be done according to the 10-20 International EEG 10-20 System for electrode placement.

DEVICE

Active HD-tDCS over V1

For HD-tDCS a 4 × 1 montage (Kessler et al., 2013), small circular electrodes (diameter 1 cm) will be used with the anode placed centrally with a current intensity of 1 mA for a total of 20 minutes (30 s ramp up/down). Hereby, the anodal electrode modulates the excitability of the targeted area left V1, whereas the other 4 electrodes return electrical currents that flow away from that area. V1 will be localised via published procedures and electrode's placement will be done according to the 10-20 International EEG 10-20 System for electrode placement.

DEVICE

Sham HD-tDCS over V5/MT or V1

Sham HD-tDCS will be delivered over left V5/MT or left V1. The same electrodes placement as well as the stimulation set-up will be used as in the active stimulation conditions, but the current will be applied for 30 s and will be ramped down (0 mA) during the rest of the session without the participants awareness. .

Trial Locations (1)

00165

RECRUITING

Bambino Gesù Hospital and Research Institute, Roma

All Listed Sponsors
lead

Bambino Gesù Hospital and Research Institute

OTHER