18
Participants
Start Date
September 27, 2023
Primary Completion Date
August 15, 2024
Study Completion Date
November 15, 2025
Ozone therapy using a device (Ozone DTA Ozone Generator, Denta Tec Dental AS, Norway)
Ozone therapy procedures will be performed immediately after non-surgical periodontal treatment and three times (every third day) within one week using a device equipped with a periodontal tip according to equipment producer recommendations. The periodontal tip will be halted 1 mm short of the pocket depth. Ozone will be applied only to the pockets; which depth is equal to or greater than 5 mm. Ozone application time to the pockets will be 30 seconds at a fixed concentration of 2,100 ppm (80% oxygen) through a connected handpiece.
Non-surgical periodontal treatment
Non-surgical periodontal treatment consists of oral hygiene instructions, full mouth supragingival scaling using hand instruments, ultrasonic devices, polishing, and subgingival debridement under local anesthesia with sharp Gracey and Universal curettes and ultrasonic instruments in a single appointment.
RECRUITING
Biruni University, Istanbul
Biruni University
OTHER