Clearance of Asymptomatic Pharyngeal Carriage of Neisseria Gonorrhoeae With or Without Ceftriaxone Treatment: Randomized Non-inferiority Study

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

254

Participants

Timeline

Start Date

September 30, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Neisseria Gonorrhoeae InfectionAsymptomatic Pharyngeal Carriage
Interventions
OTHER

Absence of antibiotic treatment

Absence of antibiotic treatment for at most 3 months after screening for asymptomatic NG pharyngeal infection (treatment if onset of symptoms related to STI or positive PCR at 3 months)

DRUG

Ceftriaxone

Ceftriaxone 1000 mg by parenteral intramuscular route, in a single dose, according to the national recommendations in force, to be repeated if pharyngeal PCR again positive for NG during follow-up

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER