The Effect of Chronic Remote Ischaemic Preconditioning on Blood Pressure in Older Adults

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 25, 2022

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
HypertensionVascular Diseases
Interventions
DEVICE

Remote Ischaemic Preconditioning

RIPC is induced by 4 cycles of 5 minutes of healthy upper limb ischaemia followed by 5 minutes reperfusion. Ischaemia is induced by inflation of a blood pressure cuff to 20mmHg above systolic blood pressure. RIPC is conducted 3 times weekly for 6-weeks. Clinic blood pressure is measured at weeks 0, 3 and 6. 24-hour blood pressure is measured at weeks 0 and 6.

DEVICE

Sham Remote Ischaemic Preconditioning

Sham RIPC is induced by 4 cycles of 5 minutes of healthy upper limb ischaemia followed by 5 minutes reperfusion. Ischaemia is induced by inflation of a blood pressure cuff to 20mmHg. RIPC is conducted 3 times weekly for 6-weeks. Clinic blood pressure is measured at weeks 0, 3 and 6. 24-hour blood pressure is measured at weeks 0 and 6.

Trial Locations (1)

DE22 3DT

School of Medicine, Royal Derby Hospital Site, University of Nottingham, Derby

All Listed Sponsors
lead

University of Nottingham

OTHER