19
Participants
Start Date
December 7, 2022
Primary Completion Date
August 1, 2023
Study Completion Date
September 1, 2023
Injection of peptide p5+14 radiolabeled with iodine-124 (124I-AT-01)
124I-AT-01 (124I-p5+14, iodine-124I evuzamitide) is a a novel iodine-124 (124I) labeled 45 L-amino acid peptide suitable for PET/CT imaging that has been shown to bind systemic amyloid deposits of diverse types in all organs, including the heart. The peptide binds amyloid through multivalent electrostatic interactions with the amyloid fibril and ubiquitous heparan sulfate proteoglycans.
University of Tennessee Graduate School of Medicine, Knoxville
University of Tennessee Graduate School of Medicine
OTHER