A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED

PHASE2RecruitingINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

August 17, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Persistent Corneal Epithelial Defect
Interventions
DRUG

lufepirsen high dose

Lufepirsen is an unmodified connexin43 antisense oligonucleotide.

DRUG

Vehicle

Matching vehicle without lufepirsen.

DRUG

lufepirsen low dose

Lufepirsen is an unmodified connexin43 antisense oligonucleotide.

Trial Locations (28)

19004

RECRUITING

Glaukos Investigative Site, Bala-Cynwyd

28150

RECRUITING

Glaukos Investigative Site, Shelby

30339

RECRUITING

Glaukos Investigative Site, Atlanta

33143

RECRUITING

Glaukos Investigative Site, South Miami

33907

RECRUITING

Glaukos Investigative Site, Fort Myers

34209

RECRUITING

Glaukos Investigative Site, Bradenton

36301

RECRUITING

Glaukos Investigative Site, Dothan

37215

RECRUITING

Glaukos Investigative Site, Nashville

46032

RECRUITING

Glaukos Investigative Site, Carmel

48026

RECRUITING

Glaukos Investigative Site, Fraser

53226

RECRUITING

Glaukos Investigative Site, Milwaukee

53705

RECRUITING

Glaukos Investigative Site, Madison

64133

RECRUITING

Glaukos Investigative Site, Kansas City

64154

RECRUITING

Glaukos Investigative Site, Kansas City

77025

RECRUITING

Glaukos Investigative Site, Houston

78209

RECRUITING

Glaukos Investigative Site, San Antonio

80924

RECRUITING

Glaukos Investigative Site, Colorado Springs

81501

RECRUITING

Glaukos Investigative Site, Grand Junction

90505

RECRUITING

Glaukos Investigative Site, Torrance

94954

RECRUITING

Glaukos Investigative Site, Petaluma

07650

RECRUITING

Glaukos Investigative Site, Palisades Park

Unknown

RECRUITING

Glaukos Investigative Site, Mainz

RECRUITING

Glaukos Investigative Site, München

RECRUITING

Glaukos investigative Site, Messina

RECRUITING

Glaukos Investigative Site, Barcelona

RECRUITING

Glaukos Investigative Site, Madrid

RECRUITING

Glaukos Investigative Site, Seville

RECRUITING

Glaukos Investigative Site, Zaragoza

Sponsors
All Listed Sponsors
lead

Glaukos Corporation

INDUSTRY