High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

February 5, 2024

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2028

Conditions
HIVArterial StiffnessCognitive Dysfunction
Interventions
BEHAVIORAL

High-Intensity Interval Training

Following a 5-minute warm-up at 50% VO2peak, high and moderate-intensity exercise bouts alternate, progressing to five bouts of 4-minute high-intensity exercise (90% VO2peak), alternating with four 3-minute bouts of moderate-intensity exercise (50% VO2peak) by week 8, followed by a 5 minute cool-down. The total exercise time is 42 minutes.

BEHAVIORAL

Continuous Moderate Exercise

Following a 4 minute warm-up at 50% VO2peak, the participant walks for up to 42 continuous minutes at 60% VO2peak, followed by a 4 minute cool-down. The total exercise time is 50 minutes.

Trial Locations (1)

35205

RECRUITING

University of Alabama at Birmingham, Birmingham

All Listed Sponsors
lead

University of Alabama at Birmingham

OTHER