Does Human Skeletal Muscle Possess an Epigenetic Memory of Testosterone?

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

September 1, 2024

Primary Completion Date

July 30, 2025

Study Completion Date

September 30, 2025

Conditions
Healthy AgingAge-Related SarcopeniaTestosterone Deficiency
Interventions
DRUG

Saline

Two placebo injections one at baseline and one week 3.

DRUG

Testosterone Undecanoate

Two testosterone undecanoate injections, 1000 mg/4 ml at baseline, 500 mg/2 ml at week 3.

DRUG

Saline + Resistance exercise training

Two placebo injections one at baseline and one week 3 and10 weeks of supervised, structured, progressive resistance training.

DRUG

Testosterone Undecanoate + Resistance exercise training

Two testosterone undecanoate injections, 1000 mg/4 ml at baseline, 500 mg/2 ml at week 3 and 10 weeks of supervised, structured, progressive resistance training.

Trial Locations (1)

0863

RECRUITING

Norwegian School of Sport Sciences, Oslo

All Listed Sponsors
collaborator

Oslo University Hospital

OTHER

lead

Norwegian School of Sport Sciences

OTHER