200
Participants
Start Date
December 20, 2023
Primary Completion Date
May 31, 2026
Study Completion Date
August 31, 2026
Tinengotinib 8 mg
Subjects randomized to receive tinengotinib will receive a starting dose of either 8 mg QD., self-administered orally QD in 28-day cycles.
Tinengotinib 10 mg
Subjects randomized to receive tinengotinib will receive a starting dose of either10 mg QD., self-administered orally QD in 28-day cycles.
Physician's Choice
For subjects receiving FOLFOX or FOLFIRI, the subject will receive treatment every two weeks, with two administrations per each 28-day cycle.
RECRUITING
National Taiwan University Hospital, Taipei
NOT_YET_RECRUITING
Candiolo Cancer Institute - FPO IRCCS, Candiolo
RECRUITING
Taipei Veterans General Hospital, Taipei
RECRUITING
CHA Bundang Medical Center, Seongnam-si
RECRUITING
Roswell Park Comprehensive Cancer Center, Buffalo
RECRUITING
Gachon University Gil Medical Center, Incheon
RECRUITING
University of Virginia Cancer Center, Charlottesville
RECRUITING
Messino Cancer Centers, Asheville
RECRUITING
Mount Sinai Comprehensive Cancer Center, Miami Beach
RECRUITING
Tennessee Oncology- Nashville, Nashville
RECRUITING
Vanderbilt-Ingram Cancer Center, Nashville
NOT_YET_RECRUITING
Taichung Veterans General Hospital, Taichung
RECRUITING
Kyungpook National University Hospital, Daegu
RECRUITING
University Hospitals Cleveland Medical Center, Cleveland
NOT_YET_RECRUITING
University of Michigan, Ann Arbor
RECRUITING
Inje University Haeundae Paik Hospital, Busan
NOT_YET_RECRUITING
Henry Ford, Detroit
RECRUITING
Dong-A University Hospital, Busan
RECRUITING
Gyeongsang National University Hospital, Jinju
NOT_YET_RECRUITING
Medical College of Wisconsin, Milwaukee
NOT_YET_RECRUITING
University of Minnesota- Masonic Cancer Center, M Health Fairview, Minneapolis
RECRUITING
Chonnam National University Hwasun Hospital, Hwasun
RECRUITING
The University of Chicago Hospitals, Chicago
NOT_YET_RECRUITING
University of Texas Southwestern Medical Center, Dallas
NOT_YET_RECRUITING
Texas Oncology-Sammons Cancer Center, Dallas
RECRUITING
The University of Texas MD Anderson Cancer Center, Houston
RECRUITING
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City
RECRUITING
The University of Kansas Cancer Center, Westwood, Los Angeles
RECRUITING
UCLA Medical Center, Santa Monica
RECRUITING
Stanford Cancer Center, Stanford
RECRUITING
Chang Gung Memorial Hospital CGMH - Kaohsiung Branch, Kaohsiung City
NOT_YET_RECRUITING
UMass Memorial Medical Center, Worcester
RECRUITING
Ordensklinikum Linz GmbH, Linz
NOT_YET_RECRUITING
Landesklinikum Wiener Neustadt, Wiener Neustadt
NOT_YET_RECRUITING
Universitair Ziekenhuis Antwerpen, Antwerp
NOT_YET_RECRUITING
Universitair Ziekenhuis Gent, Ghent
NOT_YET_RECRUITING
Universitair Ziekenhuis Leuven, Leuven
NOT_YET_RECRUITING
Institut Sainte Catherine - Institut du Cancer Avignon Provence, Avignon
NOT_YET_RECRUITING
Centre Hospitalier Régional Universitaire de Besançon, Besançon
NOT_YET_RECRUITING
Hopital Beaujon, Clichy
NOT_YET_RECRUITING
Hopital Franco-Britannique - Fondation Cognacq-Jay, Levallois-Perret
NOT_YET_RECRUITING
Clinique de la Sauvegarde, Lyon
NOT_YET_RECRUITING
Centre Hospitalier Universitaire de Montpellier, Montpellier
NOT_YET_RECRUITING
Hopital Saint Antoine, Paris
NOT_YET_RECRUITING
Institut de Cancerologie Gustave Roussy, Villejuif
RECRUITING
Krebszentrum Reutlingen, Baden
RECRUITING
Krankenhaus Nordwest gGmbH, Frankfurt
NOT_YET_RECRUITING
Asklepios Klinik Altona, Hamburg
NOT_YET_RECRUITING
Medizinische Hochschule Hannover, Hanover
RECRUITING
Universitaetsklinikum Heidelberg (UKHD) - Nationales Centrum fuer Tumorerkrankungen Heidelberg (NCT), Heidelberg
NOT_YET_RECRUITING
Ludwig-Maximilians-Universität München Kum, München
RECRUITING
Clinica Oncologica, Ospedali Riuniti Umberto 1, Ancona
RECRUITING
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola
NOT_YET_RECRUITING
Istituto Europeo di Oncologia IRCCS, Milan
NOT_YET_RECRUITING
ASST Grande Ospedale Metropolitano Niguard, Milan
NOT_YET_RECRUITING
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
NOT_YET_RECRUITING
Azienda Ospedaliera Universitaria Luigi Vanvitelli, Napoli
RECRUITING
Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli
NOT_YET_RECRUITING
Azienda Ospedaliera Universitaria di Parma, Parma
NOT_YET_RECRUITING
Azienda Ospedaliero-Universitaria Pisana, Pisa
RECRUITING
Humanitas Research Hospital, Rozzano
NOT_YET_RECRUITING
Azienda Ospedaliera Universitaria Senese Policlinico Le Scotte, Siena
RECRUITING
AOUI Verona - Ospedale Borgo Roma, Verona
NOT_YET_RECRUITING
Centrum Onkologii-Instytut im. Marii Skłodowskiej-Curie, Warsaw
NOT_YET_RECRUITING
Centro Hospitalar Lisboa Norte CHLN EPE - Hospital de Santa Maria, Lisbon
NOT_YET_RECRUITING
Fundação Champalimaud, Lisbon
RECRUITING
Hospital Clínic de Barcelona, Barcelona
RECRUITING
Hospital Universitari Vall d´Hebron, Barcelona
RECRUITING
Hospital Universitario Reina Sofa, Córdoba
RECRUITING
Clinica Universidad de Navarra, Madrid
RECRUITING
HM Hospital Universitario Madrid Sanchinarro - CIOCC, Madrid
RECRUITING
Hospital General Universitario Gregorio Maranon, Madrid
RECRUITING
Hospital Universitario 12 de octubre, Madrid
RECRUITING
Hospital Universitario Fundacion Jimenez Diaz, Madrid
RECRUITING
Hospital Universitario Ramón y Cajal, Madrid
RECRUITING
Clinica Universidad de Navarra, Pamplona
NOT_YET_RECRUITING
Hospital Clinico Universitario de Santiago de Compostela, Santiago de Compostela
NOT_YET_RECRUITING
Hospital Universitario Miguel Servet, Zaragoza
NOT_YET_RECRUITING
Royal Marsden Hospital NHS, London
NOT_YET_RECRUITING
UCG-1st floor central, London
NOT_YET_RECRUITING
The Christie NHS Foundation Trust - Christie Hospital, Manchester
NOT_YET_RECRUITING
Nottingham University Hospitals NHS Trust, Nottingham
NOT_YET_RECRUITING
Amsterdam UMC, location AMC, Amsterdam
NOT_YET_RECRUITING
Seoul National University Hospital, Seoul
RECRUITING
Yonsei University Health System - Severance Hospital, Seoul
RECRUITING
Samsung Medical Center, Seoul
RECRUITING
Korea University Guro Hospital, Seoul
TransThera Sciences (Nanjing), Inc.
INDUSTRY