Effect of Orexin System on Nicotine Addiction and Its Neural Mechanism

NANot yet recruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

July 31, 2027

Study Completion Date

July 31, 2027

Conditions
Tobacco Use Disorder
Interventions
BEHAVIORAL

extinction training (nicotine cues)

extinction training: were repeatedly presented with nicotine cue picture stimuli for extinction training, which lasted for 25 minutes.

BEHAVIORAL

extinction training (neutral cues)

extinction training: were repeatedly presented with neutral cue picture stimuli for extinction training, which lasted for 25 minutes.

BEHAVIORAL

Time-restricted smoking cessation

Limiting cigarette intake within each day to a shorter interval, thus, no cigarette from 18:00 pm to 10:00 am.

BEHAVIORAL

Time-restricted fasting

Limiting food intake within each day to a shorter interval, thus, no food from 18:00 pm to 10:00 am.

BEHAVIORAL

Time-restricted fasting with food supplemnet

Limiting food intake within each day to a shorter interval, thus, no food from 18:00 pm to 8:00 am, then supplied with breakfast.

Trial Locations (1)

518118

Shenzhen Kangning Hospital, Shenzhen

All Listed Sponsors
lead

Shenzhen Kangning Hospital

OTHER

NCT05947162 - Effect of Orexin System on Nicotine Addiction and Its Neural Mechanism | Biotech Hunter | Biotech Hunter