NCT05946798View on ClinicalTrials.gov

Role of NADPH Oxidase in Microvascular Dysfunction Following GDM

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

August 30, 2023

Primary Completion Date

June 30, 2027

Study Completion Date

June 1, 2028

Conditions
Gestational DiabetesOxidative StressVascular Endothelial Function
Interventions
DRUG

Acetylcholine

acetylcholine is perfused at 10 ascending concentrations (10\^-10M - 10\^-1 M) for 5 minutes each

DRUG

Insulin aspart

insulin aspart is perfused at 5 ascending concentrations (10\^-8M - 10\^-4 M) for 10 minutes each

Trial Locations (1)

52242

RECRUITING

University of Iowa, Iowa City

All Listed Sponsors
lead

Anna Stanhewicz, PhD

OTHER