53
Participants
Start Date
July 13, 2023
Primary Completion Date
March 31, 2026
Study Completion Date
January 31, 2027
Futibatinib
TAS-120 20 mg tablets, oral; once daily
Pembrolizumab
400 mg once every 6-week-cycle, via IV infusion.
Cisplatin
80 mg/m\^2 Q3W via IV infusion, as part of investigator's choice FP chemotherapy
5-FU
"4000 mg/m\^2 Q3W via IV infusion, as part of investigator's choice FP chemotherapy or 400 mg/m\^2 Q2W via bolus IV infusion followed by 2400 mg/m\^2 Q2W via continuous IV infusion, as part of investigator's choice mFOLFOX6 chemotherapy.~2400 mg/m\^2 Q2W via continuous IV infusion, as part of investigator's choice mFOLFOX6 chemotherapy.~2400 mg/m\^2 Q2W via continuous IV infusion, as part of mFOLFIRINOX chemotherapy."
Oxaliplatin
85 mg/m\^2 Q2W via IV infusion, as part of mFOLFIRINOX or mFOLFOX6 chemotherapy. 2400 mg/m\^2 Q2W via continuous IV infusion, as part of mFOLFIRINOX chemotherapy.
Leucovorin
400 mg/m\^2 Q2W as part of mFOLFIRINOX or mFOLFOX6 chemotherapy.
Levoleucovorin
200 mg/m\^2 Q2W as part of investigator's choice mFOLFOX6 chemotherapy.
Irinotecan
150 mg/m\^2 Q2W as part of mFOLFIRINOX chemotherapy.
NYU Langone, New York
Roswell Park Comprehensive Cancer Center (RPCCC) (Roswell Park Cancer Institute (RPCI)), Buffalo
Alliance Cancer Specialists, Horsham
Inova Schar Cancer Institute, Fairfax
Blue Ridge Cancer Care, Roanoke
Hospital Universitario 12 de Octubre, Madrid
Mount Sinai Comprehensive Cancer Center, Miami Beach
Moffitt Cancer Center and Research Institute, Tampa
Vanderbilt University Medical Center, Nashville
Gabrail Cancer Center Research LLC, Canton
Henry Ford Health System, Detroit
Gundersen Lutheran Health System, La Crosse
Universitaetsmedizin Mainz, Mainz
Centre Hospitalier Regional Universitaire de Lille, Lille
Krankenhaus Nordwest gGmbH, Frankfurt
Dallas VA Medical Center, Dallas
Rocky Mountain Cancer Centers Midtown, Denver
Centre Hospitalier Regional Universitaire Poitiers, Poitiers
University of California Los Angeles UCLA - Cancer Care - Santa Monica, Santa Monica
Virginia Mason Medical Center, Seattle
The Minniti Center - Medical Oncology and Hematology, Mickleton
Hospital Universitari Vall d'Hebron, Barcelona
Taiho Oncology, Inc.
INDUSTRY