150
Participants
Start Date
August 1, 2023
Primary Completion Date
July 1, 2025
Study Completion Date
December 1, 2025
paired taVNS
The stimulator will be placed on the left ear of the patient. While the patient performs the action training, the EMG signal feature evoked by the action will trigger an electrical stimulation of the transcutaneous auricular vagus nerve. The amplitude of the electrical stimulation will be adjusted under the patient's pain threshold. The intervention will be performed daily for 14 days.
Unpaired taVNS
The stimulator will be placed on the patient's left ear. Patients will receive taVNS with pulses every 5-7 seconds. Following the stimulation, motor training will be performed. The motor training will be identical to that of the paired group. The amplitude of the electrical stimulation will be adjusted under the patient's pain threshold. The intervention will be performed daily for 14 days.
Sham taVNS
The stimulator will be placed on the patient's left ear. The amplitude of the electrical stimulation will be adjusted at 0 mA. The intervention will be performed daily for 14 days.
RECRUITING
Zhujiang Hospital of Southern Medical University, Guangzhou
Zhuhai Fudan Innovation Institute
UNKNOWN
BrainClos Co., LTD.
UNKNOWN
Qiuyou Xie
OTHER