Phase II Study of Intensity Modulated Radiotherapy in Dose Painting for Sinus Carcinomas After Endoscopic Surgery

PHASE2RecruitingINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

March 11, 2024

Primary Completion Date

January 31, 2028

Study Completion Date

March 31, 2029

Conditions
Tumor, Solid
Interventions
RADIATION

Radiotherapy in painting dose on histoscannographic mapping

"The target volumes to be delineated are as follows:~* High-risk CTV (Clinical Target Volume), corresponding to all initially invaded areas, as identified by comparison between the operative report and the anatomo-pathological report (ideally with histo-surgical mapping).~* Low-risk CTV, corresponding to naso-sinusal structures not initially invaded but at risk of recurrence, and located close to the high-risk target volume, including at least 5 mm around the high-risk volume and excluding non-risk areas (muscle, bone)."

RADIATION

Standard pan-sinusal Radiotherapy

"The target volumes to be delineated are as follows:~* High-risk CTV, including the entire post-operative cavity,~* Low-risk CTV, adapted from the recommendations described by Lapeyre (Cancer/Radiotherapy 2005), and including at least 5 mm around the high-risk volume, excluding non-risk areas (muscle, bone)."

Trial Locations (3)

Unknown

RECRUITING

Centre Francois Baclesse, Caen

NOT_YET_RECRUITING

CHU CAEN, Caen

NOT_YET_RECRUITING

Centre Oscar Lambret, Lille

All Listed Sponsors
lead

Centre Francois Baclesse

OTHER