Effects of Subconscious Memory Extinction in Patients With Alcohol Dependence and Its Mechanism

NARecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

July 20, 2023

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Alcohol Use Disorder
Interventions
BEHAVIORAL

Very brief extinction

"The very brief extinction presents a very short (33ms) repetitive sequence of alcohol cues, followed by a masking stimulus(117ms), which masks the alcohol cues. In the case of repeated exposure to alcohol stimulation, the response to the stimulation is desensitized at the level of unconscious processing."

BEHAVIORAL

Clearly visible extinction

"The clearly visible extinction presents a repetitive sequence of alcohol cues(150ms) without a masking stimulus. In the case of repeat exposure to alcohol stimulation, the response to the stimulation is desensitized at the level of conscious processing."

BEHAVIORAL

Very brief neutral extinction

"The very brief neutral extinction presents a very short (33ms) repetitive sequence of neutral cues, followed by a masking stimulus(117ms), which masks the neutral cues. In the case of repeated exposure to neutral stimulation, the response to the stimulation is desensitized at the level of unconscious processing."

Trial Locations (1)

518118

RECRUITING

Shenzhen Kangning Hospital, Shenzhen

All Listed Sponsors
lead

Shenzhen Kangning Hospital

OTHER