Dexmedetomidine or Lidocaine for Lessening the Hemodynamic Responses to Laryngoscopy and Intubation

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

July 12, 2023

Primary Completion Date

November 5, 2023

Study Completion Date

January 3, 2024

Conditions
Anesthesia Intubation Complication
Interventions
DRUG

Dexmedetomidine nebulization

The patient will receive nebulized dexmedetomidine via face mask nebulizer 10 minutes before induction of general anesthesia.

DRUG

Lidocaine nebulization

The patient will receive nebulized lidocaine 4% (3 mg /kg) 10 minutes before induction of general anesthesia.

DRUG

Dexmedetomidine IV

The patient will receive intravenous infusion via a syringe pump of dexmedetomidine (1 ml= 4mcg) started at a dose of 1 mcg/kg 20 minutes before induction of general anesthesia.

DRUG

Lidocaine IV

The patient will receive 1.5 mg/kg lidocaine 2% (1 ml = 20mg) completed to 10 ml with normal saline 0.9% intravenous 90 seconds before induction of general anesthesia.

Trial Locations (1)

055

Faculty of medicine, Zagazig University, Zagazig

All Listed Sponsors
lead

Zagazig University

OTHER_GOV