Cerebral Flow-metabolism Coupling During Adult Surgery

PHASE4RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

October 3, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Anesthesia
Interventions
DRUG

Propofol

Patient will receive propofol as their maintenance agent during surgery. The typical dose is 150-200 mg/kg/min.

DRUG

Sevoflurane

Patient's anesthesia will be maintained with 1 MAC of sevoflurane during surgery.

DRUG

Ephedrine

The patient will receive ephedrine infusion as the primary vasopressor of choice. The typical dose of ephedrine infusion is 10-50 mg/hr (dilution 2 mg/ml).

DRUG

Phenylephrine

Patient will receive phenylephrine infusion as the primary vasopressor of choice. The typical dose of phenylephrine infusion is 10-40 mcg/min (dilution 100 mcg/ml).

Trial Locations (1)

N6A 5A5

RECRUITING

London Health Sciences Centre, London

All Listed Sponsors
lead

Jason Chui

OTHER