Efficacy and Safety of Moisturising Cream with or Without Vitamin E and Urea Cream in Palmar-plantar Erythrodysesthesia

The vitamin E moisturising cream contains 3% w/w of palm-oil-derived vitamin E concentrate, consisting of the following isomers: alpha-tocopherol, alpha-tocotrienol, beta-tocotrienol, gamma-tocotrienol, and delta-tocotrienol. This formula provides a total of 1.2g tocotrienols per 100g product.

This moisturising cream is a similar moisturising cream but without the addition of the vitamin E concentrate

Urea cream (10%w/w) is used as the standard of care for PPE.