Metabolism in the Human Brain Following Consumption of a Keto-ester in Alcohol Use Disorder (AUD) With Proton Magnetic Resonance Spectroscopic Imaging (MRSI)

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

August 14, 2023

Primary Completion Date

May 15, 2024

Study Completion Date

May 15, 2024

Conditions
BHB TransportAlcohol Use Disorder
Interventions
OTHER

Keto-ester followed by Magnetic Resonance Spectroscopic Imaging (MRSI) scans

Following baseline scans, the participant will orally consume the keto-ester, for subsequent scans which will include repeated BHB MRSI acquisitions to dynamically measure BHB labeling in the brain, followed by a final GABA MRSI acquisition.

Trial Locations (1)

06519

The Anlyan Center (TAC), New Haven

All Listed Sponsors
lead

Yale University

OTHER

NCT05937893 - Metabolism in the Human Brain Following Consumption of a Keto-ester in Alcohol Use Disorder (AUD) With Proton Magnetic Resonance Spectroscopic Imaging (MRSI) | Biotech Hunter | Biotech Hunter