Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

NARecruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

June 20, 2025

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2026

Conditions
Nicotine Use Disorder
Interventions
OTHER

E-liquid coolant (No WS-3) for non-menthol (1)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants without WS-3.

OTHER

E-liquid coolant (No WS-3) for low menthol (1)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants without WS-3.

OTHER

E-liquid coolant (No WS-3) for high menthol (1)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants without WS-3.

OTHER

E-liquid coolant (Low WS-3) for non-menthol (2)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-3 concentration.

OTHER

E-liquid coolant (Low WS-3) for low menthol (2)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-3 concentration.

OTHER

E-liquid coolant (Low WS-3) for high menthol (2)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-3 concentration.

OTHER

E-liquid coolant (High WS-3) for non-menthol (3)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-3 concentration.

OTHER

E-liquid coolant (High WS-3) for low menthol (3)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-3 concentration.

OTHER

E-liquid coolant (High WS-3) for high menthol (3)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-3 concentration.

OTHER

E-liquid coolant (Low WS-23) for non-menthol (4)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-23 concentration.

OTHER

E-liquid coolant (Low WS-23) for low menthol (4)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-23 concentration.

OTHER

E-liquid coolant (Low WS-23) for high menthol (4)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-23 concentration.

OTHER

E-liquid coolant (High WS-23) for non-menthol (5)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-23 concentration.

OTHER

E-liquid coolant (High WS-23) for low menthol (5)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-23 concentration.

OTHER

E-liquid coolant (High WS-23) for high menthol (5)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-23 concentration.

Trial Locations (1)

06519

RECRUITING

JB Pierce Lab, New Haven

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Yale University

OTHER

NCT05932745 - Effects of Novel E-cigarette Constituents on Adults TCORS 3.0 | Biotech Hunter | Biotech Hunter