The Role of Budesonide Intrapolyp Injection in the Management of Type 2 Chronic Rhinosinusitis

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

May 1, 2021

Primary Completion Date

February 1, 2023

Study Completion Date

February 1, 2023

Conditions
Chronic Rhinosinusitis With Nasal Polyps
Interventions
DRUG

Budesonide

after application of topical vasoconstrictor packs into both nasal cavities, using 1 cc 28 gauge needle sterile syringe, one pack of budesonide ampule 0.5 mg/2ml was injected into visible polyps on both cavities 1 ml in each cavity weekly for 5 consecutive weeks

DRUG

Prednisone

patients given oral prednisone 1 mg/ kg with max. dose 70 mg/d divided into two doses for 3 days then tapered gradually for two weeks

DRUG

Saline

saline intrapolyp injection

Trial Locations (1)

37458

Kafrelsheikh University hospital, Kafrelsheikh

All Listed Sponsors
lead

Kafrelsheikh University

OTHER