Exercise Intolerance Study in Long Chain Fatty Acid Oxidation Disorders

RecruitingOBSERVATIONAL
Enrollment

50

Participants

Timeline

Start Date

August 1, 2023

Primary Completion Date

August 1, 2028

Study Completion Date

August 1, 2028

Conditions
Long-chain Fatty Acid Oxidation Disorders
Interventions
OTHER

Intermittent cardiopulmonary exercise test

Exercise test with step-change from rest to a relatively low constant workload.

OTHER

Incremental cardiopulmonary exercise test

Exercise test with incremental workload until maximal workload.

OTHER

Echography of upper leg

Determine upper leg muscle size

OTHER

Hand grip strength with hand dynamometer

Determine muscle strength

OTHER

Fill in questionnaires regarding physical activity

SQUASH, mMRC, questionnaire designed to report myopathic symptoms in LcFAOD patients.

Trial Locations (1)

1105 AZ

RECRUITING

Amsterdam UMC, location AMC, Amsterdam

All Listed Sponsors
collaborator

Stichting Stofwisselkracht

UNKNOWN

lead

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER