NCT05920109View on ClinicalTrials.gov

EffecT of eARly analGesia With Erector Spinae Plane Block to Reduce Ventilation After Severe Chest Trauma

NARecruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

October 22, 2023

Primary Completion Date

January 31, 2026

Study Completion Date

July 31, 2027

Conditions
Severe Chest Trauma
Interventions
PROCEDURE

ESP block

Patients in the experimental group will have a continuous Erector Spinae Plane Block within the first 6 hours post-admission, with a continuous 1ml/h infusion of Ropivacaine (2mg/ml) associated with a 25 ml bolus every 6h. The catheter will be used from the trauma bay to the ICU as long as possible with a dedicated infusion pump (with a bolus mode). In case of accidental catheter removal, a second introduction of ESP block catheter is allowed within the first 24 hours. In case of continuous ESP block failure (incidence \< 5% of the total experimental group), patients will be switched to the control group.

Trial Locations (14)

31059

RECRUITING

Chu Toulouse - Hopital Rangueil, Toulouse

33000

RECRUITING

CHU Bordeaux - Pellegrin, Bordeaux

37000

RECRUITING

CHRU Hôpitaux De Tours, Tours

38049

RECRUITING

CHU Grenoble Alpes, Grenoble

59000

RECRUITING

CHU de Lille, Lille

63000

RECRUITING

CHU Clermont-Ferrand, Clermont-Ferrand

69003

RECRUITING

Chu Toulouse - Hopital Purpan, Toulouse

69310

RECRUITING

Hôpital Lyon Sud, Pierre-Bénite

74370

RECRUITING

CH Annecy Genevois, Épagny

75013

RECRUITING

Hôpital Pitie Salpetriere - AP-HP, Paris

75015

RECRUITING

Hôpital Européen Georges Pompidou - AH-HP, Paris

83000

RECRUITING

Hôpital d'Instruction des Armées Sainte Anne, Toulon

92118

RECRUITING

Hopital Beaujon - AP-HP, Clichy

92140

RECRUITING

Hôpital d'instruction des armées Percy, Clamart

All Listed Sponsors
collaborator

University Hospital, Clermont-Ferrand

OTHER

lead

University Hospital, Grenoble

OTHER