Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft

PHASE4RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

October 19, 2023

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Pain, Post OperativeQuality of Life
Interventions
DRUG

Ibuprofen 600 mg

Preoperative delivery of ibuprofen per os.

DRUG

Placebo

Preoperative delivery of placebo per os.

DRUG

Acetaminophen

Both groups will be given rescue medication in the form of 1,000 mg tabs of acetaminophen every 6 hours per os as needed for pain (maximum allowed daily dose 4,000 mg per FDA) and will be allowed to receive ibuprofen or other analgesic medication as needed if pain is not controlled by acetaminophen alone. The subjects will receive the rescue medication pills at the end of the surgical appointment.

Trial Locations (1)

53233

RECRUITING

Marquette University School of Dentistry Graduate Periodontics Clinic, Milwaukee

All Listed Sponsors
lead

Marquette University

OTHER