FAMILY INHERITANCE, GENE-GENE AND GENE-ENVIRONMENT INTERACTIONS IN THE FIELD OF CARDIOVASCULAR AND RENAL DISEASES. Fifth Visit of the STANISLAS Cohort

NARecruitingINTERVENTIONAL
Enrollment

3,000

Participants

Timeline

Start Date

July 13, 2023

Primary Completion Date

July 13, 2027

Study Completion Date

July 13, 2027

Conditions
Cardiovascular DiseasesCohort StudiesGenotypeRisk FactorsNutrition
Interventions
BIOLOGICAL

Blood and urine samples

Blood and urine samples

GENETIC

Blood samples

Blood samples

OTHER

Cardiovascular assessment

Echocardiography, Lung ultrasound, pulse wave velocity, carotid stiffness and thickness, Central and peripheral blood pressure, carotid pulse pressure, abdominal aorta ultrasound, jugular vein ultrasound, liver elastography (Optional).

BEHAVIORAL

Dietary intake

Food frequency questionnaires, ''Dutch eating behaviour questionnaire'' and dietary supplement questionnaire

OTHER

Anthropometric parameters

Measurement of height, weight, abdominal circumference, hip circumference, arm circumference

OTHER

Hemodynamic parameters

Systolic pressure index measurement

OTHER

Hemodynamic parameters

Heart rate measurements, blood pressure measurements, orthostatic BP measurements

OTHER

Hemodynamic parameters

"Blood pressure measurements by unattended BP monitor over 5 min"

OTHER

Hemodynamic parameters

Electrocardiogram

BEHAVIORAL

Assessment of compliance with antihypertensive treatments for treated participants

EVALOBS scale and compliance questionnaire

OTHER

Ambulatory 24 hours measurment of blood pressure

For the first 100 patients willing to participate

BIOLOGICAL

24 hours urinary collection

For the first 100 patients willing to participate. For biobank constitution and measurement of microalbuminuria, creatininuria, osmolarity, natriuresis, kaliuresis, urea, proteinuria and urine dipstick

OTHER

General questionnaires

Collection of socio-demographic data such as age, level of education, profession, household income, smoking status, physical activity, perception of health, prematurity, height and weight at birth, family and personal history especially cardiovascular (history of stroke, myocardial infarction, heart failure, current pathologies, drugs, tobacco...)

OTHER

Women specific questionnaire

Women specific questionnaire

BEHAVIORAL

Women specific questionnaire

Women specific questionnaire

DIAGNOSTIC_TEST

NYHA dyspnea questionnaire

Determination of NYHA class.

BEHAVIORAL

Anxiety questionnaire

Assessment of anxiety

BEHAVIORAL

Epworth Sleepiness Scale

sleep quality assessment

OTHER

"A questionnaire on the perception of the management of cardiovascular risk factors"

Patient's evaluation of cardiovascular risk factors by the health system

BEHAVIORAL

A questionnaire on eating behaviors

Assessment of eating behaviors

BEHAVIORAL

A questionnaire on eating habits to determine consumer profiles

Assessement of eating habit to create a consumer profile

DIETARY_SUPPLEMENT

A questionnaire on food supplements use

Evaluation od food supplements intake

OTHER

SARS-CoV-2 Infection Questionnaire

SARS-CoV-2 Infection Questionnaire

OTHER

Instantaneous expired air analysis

Carbon monoxyde analysis in expired air

BIOLOGICAL

Capillary sampling

Capillary sampling for pollutant analysis (Optional)

Trial Locations (1)

54500

RECRUITING

CHRU de Nancy, Vandœuvre-lès-Nancy

All Listed Sponsors
lead

Central Hospital, Nancy, France

OTHER