NCT05914285View on ClinicalTrials.gov

Assessment of Salbutamol Effect on Arterial Oxygenation in COPD Patients During One-lung Ventilation

NAActive, not recruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

April 25, 2023

Primary Completion Date

June 20, 2025

Study Completion Date

July 21, 2025

Conditions
One-lung VentilationChronic Obstructive Pulmonary Disease
Interventions
DRUG

5ml of inhaled normal saline

After the initiation of OLV, 5ml of normal saline is inhaled for 20 minutes using ultrasonic nebulizer, which is connected to the inspiratory limb of the ventilator system. Arterial blood gas analysis is performed 30 minutes after the completion of drug inhalation.

DRUG

2.5mg (2.5ml) of inhaled salbutamol and 2.5ml of inhaled normal saline

After the initiation of OLV, mixture of salbutamol 2.5mg and normal saline 2.5ml is inhaled for 20 minutes using ultrasonic nebulizer, which is connected to the inspiratory limb of the ventilator system. Arterial blood gas analysis is performed 30 minutes after the completion of drug inhalation.

Trial Locations (1)

Unknown

Severance Hospital, Yonsei University Health System, Seoul

All Listed Sponsors
lead

Yonsei University

OTHER