100
Participants
Start Date
August 25, 2020
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
Spirography and assessment of pulmonary diffusion capacity
Using the Master Screen Body device you will be asked to take two series of breaths through a special tube for 2-3 minutes. Usually the procedure does not cause any discomfort
Cardiopulmonary stress test
The exercise test is performed on a bicycle ergometer Oxycon Pro. Prior to the test, special sensors for recording the electrocardiogram, a sensor to determine blood saturation, and a cuff to measure blood pressure will be glued on the body. Breathing during the test takes place through a face mask with a built-in gas analyzer sensor. The stress test is conducted up to an individual maximum (according to the age, sex, height and weight of the patient), followed by a recovery period. There is some temporary discomfort associated with performing physical activity. Dyspnea, leg fatigue, and dizziness may occur. Observation continues until full recovery of hemodynamic and gas exchange parameters, in case of appearance of unfavorable symptoms - until their disappearance.
Computed tomography of the chest organs
"CT is a method of examination based on X-rays, but unlike conventional X-rays, it gives the most complete picture of the body structure, with less radiation.~Tomography usually does not cause any unpleasant feelings and is performed in a specialized department."
Heart echocardiography
It's a specific method of ultrasound examination, which consists in examining the heart in real time and usually does not cause any unpleasant feelings
SF-36 Quality of Life Questionnaire
https://clinmedjournals.org/articles/jmdt/jmdt-2-023-figure-1.pdf
Demographic and antropometric measures
Age, sex, height. weight, body mass index (BMI)
Indicators characterizing the severity of the underlying disease
"* Severity of underlying disease (mMRC, BODE, SMRT-CO Respiratory Support Need Scale), and comorbidities (cardiovascular disease, diabetes mellitus, chronic obstructive pulmonary disease, chronic kidney disease)~* Medications taken."
Meshalkin Scientific Research Center of the Ministry of Health of Russia, Novosibirsk
Meshalkin Research Institute of Pathology of Circulation
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