NCT05906511View on ClinicalTrials.gov

PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

October 17, 2023

Primary Completion Date

June 30, 2026

Study Completion Date

August 31, 2026

Conditions
Pain, ToleranceOral vs Vaporized THCAbuse Liability
Interventions
DRUG

Dronabinol 5 MG

Dronabinol 5 mg

DRUG

Dronabinol 10 MG

Dronabinol 10mg

DRUG

2mg Purified THC in an ethanolic solution

2mg Purified THC in an ethanolic solution

DRUG

4mg Purified THC in an ethanolic solution

4mg Purified THC in an ethanolic solution

DRUG

Placebo

Oral placebo and/or vaporized saline

Trial Locations (1)

06516

RECRUITING

VA Connecticut Healthcare System, West Haven

All Listed Sponsors
collaborator

VA Connecticut Healthcare System

FED

collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Yale University

OTHER