The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease

NACompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

August 15, 2023

Primary Completion Date

September 20, 2024

Study Completion Date

September 20, 2024

Conditions
Parkinson DiseaseDeep Brain Stimulation
Interventions
OTHER

Forced and Voluntary Exercise

Participants will complete a forced exercise (FE) and voluntary exercise (VE) session. Forced exercise is a mode of high intensity exercise in which voluntary exercise rate is augmented, but not replaced. Voluntary exercise is standard stationary cycling. FE and VE exercise sessions will be Off antiparkinsonian medication. The order in which exercise session is conducted first will be randomized. Bilateral neural activity of the STN will be continuously recorded for 130 minutes (pre, during FE or VE and post-exercise).

Trial Locations (1)

44195

Cleveland Clinic, Cleveland

All Listed Sponsors
lead

Jay Alberts

OTHER

NCT05905302 - The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease | Biotech Hunter | Biotech Hunter