Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

PHASE3RecruitingINTERVENTIONAL
Enrollment

600

Participants

Timeline

Start Date

November 9, 2023

Primary Completion Date

July 30, 2027

Study Completion Date

July 30, 2027

Conditions
Neovascular Age-related Macular Degeneration
Interventions
DRUG

Intravitreal injections of 6 mg faricimab on a Treat and Extend schedule

Intravitreal injections of 6 mg faricimab on a Treat and Extend schedule

DEVICE

Intravitreal injections of 6 mg faricimab on a home optical coherence tomography-guided treatment schedule

Intravitreal injections of 6 mg faricimab on a Home OCT-guided treatment schedule

Trial Locations (57)

10021

RECRUITING

Macula Care, New York

14620

RECRUITING

Retina Associates of Western NY, P.C., Rochester

15146

RECRUITING

Retina Vitreous Consultants, Monroeville

19104

RECRUITING

The Trustees of the University of Pennsylvania, Philadelphia

21237

RECRUITING

Elman Retina Group, BA, Baltimore

21287

RECRUITING

Johns Hopkins University, Baltimore

29926

RECRUITING

Hilton Head Retina Institute, Hilton Head Island

30328

RECRUITING

Thomas Eye Group, Sandy Springs

30909

RECRUITING

Southeast Retina Center, P.C., Augusta

32209

RECRUITING

University of Florida- Jacksonville, Jacksonville

32216

RECRUITING

Florida Retina Institute, James A. Staman, MD, PA- Jacksonville, Jacksonville

33609

RECRUITING

Retina Associates of Florida, LLC, Tampa

33912

RECRUITING

National Ophthalmic Research Institute, Fort Myers

RECRUITING

National Ophthalmic Research Institute, Fort Myers

34105

RECRUITING

Argus Research Center, Inc, Naples

34233

RECRUITING

Retina Associates of Sarasota, Sarasota

34239

RECRUITING

Sarasota Retina Institute, Sarasota

37922

RECRUITING

Southeastern Retina Associates, P.C., Knoxville

44120

RECRUITING

The Cleveland Clinic Foundation DBA Cleveland Clinic Lerner College of Medicine, Cleveland

46202

RECRUITING

The Trustees of Indiana University, Indianapolis

46290

RECRUITING

Midwest Eye Institute, Indianapolis

48073

RECRUITING

Associated Retinal Consultants, P.C., Royal Oak

48202

RECRUITING

Henry Ford Health System, Detroit

48439

RECRUITING

Retina Associates of Michigan, Grand Blanc

49686

RECRUITING

Associated Retinal Consultants, Traverse City

50266

RECRUITING

Wolfe Clinic, P.C.- West Des Moines, West Des Moines

53705

RECRUITING

The Board of Regents of the University of Wisconsin System, Madison

54403

RECRUITING

Eye Clinic of Wisconsin, Wausau

57108

RECRUITING

Ophthalmology Ltd., Sioux Falls

60612

RECRUITING

Rush University Medical Center, Chicago

RECRUITING

UIC - Dept of Ophthalmology & Visual Sciences, Chicago

63128

RECRUITING

The Retina Institute, St Louis

66211

RECRUITING

Mid-America Retina Consultants, P.A., Overland Park

73013

RECRUITING

Retina Vitreous Center, Edmond

77401

RECRUITING

Retina Consultants of Texas, PA, Bellaire

78240

RECRUITING

Retinal Consultants of Texas, San Antonio

78705

RECRUITING

Austin Research Center for Retina, Austin

79424

RECRUITING

Texas Retina Associates, Lubbock

79902

RECRUITING

Southwest Retina Consultants, El Paso

90503

RECRUITING

Macula Retina Vitreous Institute, Torrance

92211

RECRUITING

Southern California Desert Retina Consultants, Inc., Palm Desert

92354

RECRUITING

Loma Linda University, Loma Linda

94598

RECRUITING

Bay Area Retina Associates A Medical Group, Walnut Creek

94609

RECRUITING

East Bay Retina Consultants, Inc., Oakland

95817

RECRUITING

UC Davis Health Eye Center, Sacramento

97239

RECRUITING

Oregon Health & Science University, Portland

97401

RECRUITING

Verum Research LLC, Eugene

97477

RECRUITING

Cascade Medical Research Institute, LLC, Springfield

91203-1971

RECRUITING

Kent W. Small, MD, AMC, Glendale

06042

RECRUITING

Retina Consultants, Manchester

33782-4418

RECRUITING

Southeast Eye Institute, P.A. dba Eye Associates of Pinellas, Pinellas Park

01432

RECRUITING

Valley Eye Physicians and Surgeons, Ayer

02215

RECRUITING

Joslin Diabetes Center, Boston

08034

RECRUITING

Associated Retinal Surgeons d/b/a Mid Atlantic Retina, Cherry Hill

77030-4101

RECRUITING

Baylor College of Medicine, Baylor Eye Physicians and Surgeons, Houston

M3C0G9

RECRUITING

Chow Berger Koushan Medicine Professional Corporation o/a Toronto Retina Institute, North YORK

M5T 2S8

RECRUITING

University Health Network, Toronto

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Eye Institute (NEI)

NIH

collaborator

Juvenile Diabetes Research Foundation

OTHER

lead

Jaeb Center for Health Research

OTHER